Like the Wisconsin Leather Company’s tannery at Two Rivers, nothing remains of the Pfister & Vogel tannery at Two Creeks. The tannery burned in 1885 and a devastating fire in 1918 destroyed much of what remained of the once prosperous village of Two Creeks. Today, part of the site of the early tannery settlement is a town park.

When the tannery opened in May of 1851, it was one of the largest in Wisconsin and the Midwest, with 134 vats for tanning 100 hides daily for harness and light stock on the ground floor and extensive drying and storage rooms on the second floor. In 1861, a second, larger tannery, 315 × 50 feet, was constructed south of  the earlier one, with 150 double vats for tanning 75 hides daily into sole leather. Bricks used for its construction came from Milwaukee.

Pfister soon held 22 land entries in section 11, 13, and 24 of the township – mostly along Lake Michigan. His holdings represented a total of 1,429.9 acres of land. With a lot of hemlock bark nearby, the business quickly developed, and employees traveled to the bustling village.